Revista da Associacao Medica Brasileira (1992)
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Rev Assoc Med Bras (1992) · Jul 2021
Observational StudyThe impact of healthcare-associated infections on COVID-19 mortality: a cohort study from a Brazilian public hospital.
This study aims to analyze the risk factors for in-hospital mortality in a cohort of patients admitted to a newly adapted intensive care unit in a public hospital in Rio de Janeiro. ⋯ In this cohort, the strongest risk factor for in-hospital death was the development of nosocomial septic shock. Healthcare-associated infections have a significant impact on mortality rates. Therefore, to have a better outcome, it is important to consider not only the availability of beds but also the way healthcare is delivered.
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Rev Assoc Med Bras (1992) · Jul 2021
Observational StudyClinical evolution of a severe asthmatics group in the use of immunobiological therapy in a Brazilian Public Hospital.
A small portion of the asthmatic population (3.6%) has severe asthma (SA), presenting high morbimortality rates and demanding more financial resources than other asthmatic populations. The use of immunobiological therapy is an effective tool in controlling symptoms, decreasing the number of exacerbations, and reducing the use of systemic corticosteroids in these patients. In Brazil, epidemiological data regarding this asthmatic population using immunobiologicals and their evolution are scarce. ⋯ The use of omalizumab and mepolizumab as additional therapy in SA provided a significant improvement in the ACT and allowed the dose reduction of systemic corticosteroids, without significant improvement in FEV1 and in the frequency of severe exacerbations.
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Rev Assoc Med Bras (1992) · Jul 2021
Observational StudyPrognostic factors in triple-negative breast cancer: a retrospective cohort.
Triple-negative breast cancer (TNBC) is characterized by lack of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 (HER2) expression and accounts for 15-20% of all breast cancers. This study aims to analyze prognostic factors related to a reduction in overall survival (OS), disease-free survival (DFS), and risk of mortality and recurrence in TNBC. ⋯ Advanced clinical stage, positive sentinel lymph node, axillary node involvement, surgical treatment with mastectomy, and higher residual cancer burden were related to a significant reduction in OS and DFS and increased risk of mortality and recurrence in TNBC.
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Rev Assoc Med Bras (1992) · Jul 2021
Suboptimal health status of nurses in Wuhan, China during the COVID-19 outbreak.
This study analyzes the suboptimal health status (SHS) and influencing factors of nurses in Wuhan Hospital, China during the coronavirus disease 2019 (COVID-19) outbreak. ⋯ First-line nurses have poor suboptimal health status in Wuhan.
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Rev Assoc Med Bras (1992) · Jul 2021
Impact of the COVID-19 pandemic on the development of burnout syndrome in frontline physicians: prevalence and associated factors.
To evaluate the prevalence of burnout syndrome (BS) in physicians working during the COVID-19 pandemic in Paraíba and to investigate the association between BS and the sociodemographic and labor variables of these professionals. ⋯ This case series found a positive association between the development of BS and medical action on the front line of the COVID-19 pandemic in Paraíba.