Revista da Associacao Medica Brasileira (1992)
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Rev Assoc Med Bras (1992) · Sep 2022
Assessment of dynamic thiol-disulfide homeostasis in patients with lipoid proteinosis (Urbach-Wiethe syndrome).
Lipoid proteinosis is a rare autosomal recessive genetic dermatological disease that occurs due to the accumulation of hyaline material in the skin and mucous membranes. This study aimed to investigate whether dynamic thiol-disulfide homeostasis is a new marker of oxidative stress in patients suffering from lipoid proteinosis. ⋯ Impaired dynamic thiol-disulfide homeostasis was observed in lipoid proteinosis patients, suggesting that thiol-disulfide homeostasis may have a role in the pathogenesis of this disease.
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Rev Assoc Med Bras (1992) · Sep 2022
A simple method for clinical implications of pain; comprehensive geriatric assessment.
The effect of chronic pain on the elderly population is enormous in terms of both human suffering and cost. This study aimed to investigate the factors associated with chronic low back pain in older adults by performing a comprehensive geriatric assessment. ⋯ Chronic pain is common and independently associated with poor sleep quality, an increased number of diseases, and female gender. The results of our study may guide pain management in older individuals.
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Rev Assoc Med Bras (1992) · Sep 2022
Observational StudyCharacteristics and outcomes of COVID-19 patients assisted by intensivists and nonintensivists.
The aim of this study was to assess the outcomes of critically ill patients with COVID-19 in an intensive care unit seen by a care team formed by intensive and nonintensive physicians and treatment guided by processes and protocols linked to the "choosing wisely" concept, comparing them with similar data recently published. ⋯ Patients admitted for acute respiratory syndrome due to SARS-CoV-2 are severe and have a high mortality rate, mainly if submitted to invasive mechanical ventilation. The emergence of acute renal failure marks an especially severe subgroup with increased mortality. Processes and protocols linked to the "choosing-wisely" concept seemed to significantly benefit our intensive care unit since it had a large contingent of nonspecialist physicians.
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Rev Assoc Med Bras (1992) · Sep 2022
Role of apparent diffusion coefficient measurement in differentiating histological subtypes of brain metastasis of lung cancer.
The aim of this study was to investigate the role of apparent diffusion coefficient of diffusion-weighted imaging in differentiating histological subtypes of brain metastasis of lung cancer. ⋯ Minimum apparent diffusion coefficient, mean apparent diffusion coefficient, normalized apparent diffusion coefficient, and apparent diffusion coefficient of edema around metastasis can differentiate histological subtypes of brain metastasis of lung cancer.
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Rev Assoc Med Bras (1992) · Sep 2022
Prognostic value of the TyG index for in-hospital mortality in nondiabetic COVID-19 patients with myocardial injury.
The purpose of this study was to explore the efficacy of the triglyceride glucose (TyG) index on in-hospital mortality in nondiabetic coronavirus disease 2019 (COVID-19) patients with myocardial injury. ⋯ The TyG index might be used to identify high-risk nondiabetic COVID-19 patients with myocardial damage.