Revista da Associacao Medica Brasileira (1992)
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Rev Assoc Med Bras (1992) · Aug 2022
Effects of perilipin-5 on lipid metabolism and high-sensitivity cardiac troponin I.
Heart attack is one of the most common causes of sudden death in adults. Therefore, early detection of heart attack and investigation of potential new biomarkers are of great importance. We investigated whether perilipin-5 is a potential biomarker by examining changes in perilipin-5 serum levels along with high-sensitivity cardiac troponin I during a heart attack. ⋯ Our results showed that perilipin-5 together with high-sensitivity cardiac troponin I could be a promising biomarker in heart attack.
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Rev Assoc Med Bras (1992) · Aug 2022
Effectiveness of peripheral nerve blockage on the symptoms of both diseases in patients with fibromyalgia and chronic migraine coexistence.
Peripheral nerve blockage treatments reduce central sensitization and are effective in patients with migraine. We wanted to evaluate the efficacy of peripheral nerve blockage in patients with fibromyalgia and migraine whose etiology may be responsible for central sensitization, and their associations are common. ⋯ Peripheral nerve blockage has been found to be an effective treatment for the symptoms of both diseases in patients with migraine and fibromyalgia coexistence.
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Rev Assoc Med Bras (1992) · Aug 2022
Urethral monopolar cauterization: alternative infravesical obstruction model in male rats.
We aimed to determine which method gives the most consistent results between urethral monopolar cauterization and standard urethral partial ligation methods for the urethral obstruction model. ⋯ The needle-tipped monopolar cauterization of the posterior urethra may be the method of choice for creating a chronic infravesical obstruction model of infravesical obstruction in male rats.
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[This corrects the article doi: 10.1590/1806-9282.20220268].
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Rev Assoc Med Bras (1992) · Aug 2022
Vitamin C (Ascorbic acid) protects from neuropathy caused by cisplatin, through enhanced heat shock protein-70 and reduced oxidant effect.
We aimed to determine whether vitamin C has a protective effect on cisplatin-induced neuropathy in rats. ⋯ We demonstrated the ameliorated effects of vitamin C on cisplatin-induced neuropathy through increased heat shock protein-70, nerve growth factor levels, and reduced inflammatory and oxidant effects. The results are promising to improve the neurotoxic effects of cisplatin in cancer patients.