Revista da Associacao Medica Brasileira (1992)
-
Rev Assoc Med Bras (1992) · Nov 2021
High serum 8-hydroxy-2'-deoxyguanosine levels predict DNA damage and aging in professional divers.
Reactive oxygen species and oxygen free radicals cause oxidative damage to lipids, proteins, and cell DNA in the cell membrane. Although many DNA products are produced during oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine (8-OHdG) is the most common one, since it can be produced in in vivo environment. In recent years, diving has been done quite frequently for business and sports purposes all over the world. Increased environmental pressure in diving leads to hyperoxia and causes oxidative stress. ⋯ It was found that air dives caused an increase in serum 8-hydroxy-2'-deoxyguanosine levels, leading to acute oxidative stress and aging. However, there is no chronic side effect, according to the study of samples taken from the control group. This was thought to be due to the relative sedentary life of the control group. The duration of the effect or the ability to return to normal values should be investigated with further studies planned with large populations.
-
Rev Assoc Med Bras (1992) · Nov 2021
An evaluation of people's knowledge of adult vaccination information level and attitudes during the pandemic Era.
This research was carried out to evaluate people's knowledge of adult vaccination and their attitude and to observe the effect of the pandemic era on this situation. ⋯ As a result, it seems that we are far from the goals set by the health authorities for adult vaccination. We observed that the COVID-19 pandemic raised awareness toward pneumococcus and influenza vaccines and interest toward adult vaccinations and at the same time changed the thoughts against adult vaccinations.
-
Rev Assoc Med Bras (1992) · Nov 2021
Evaluation of magnetic resonance imaging findings in adhesive capsulitis: which quantitative findings are most valuable?
This study aims to investigate magnetic resonance imaging (MRI) findings in adhesive capsulitis (AC) and determine the most valuable MRI finding in diagnosis using easily applied quantitative methods. ⋯ According to the results obtained in this study, IGHL=4 mm, RI=3.6 mm, SGHL=2.0 mm, and CHL=4.6 mm can support the diagnosis of AC. Using the quantitative values in diagnosis can provide objective criteria and prevent variability among interpreters.
-
Rev Assoc Med Bras (1992) · Nov 2021
Advanced ankylosing spondylitis: a multisite, multimodality densitometric analysis for investigation of bone loss in the axial and appendicular skeleton.
The aim of this study was to investigate if there is a bias in bone mineral density measurements among major densitometric techniques across multiple skeletal sites. ⋯ Low bone mineral density is prevalent in advanced ankylosing spondylitis patients, predominating in the spine. Bone mineral density measurements have systematic differences when compared to each other. Knowledge of these offsets is useful for improved diagnosis of regional bone loss that allows for targeted treatment of osteoporosis. Three-dimensional quantitative computed tomography is more suitable for evaluating spinal osteoporosis in advanced ankylosing spondylitis than dual-energy X-ray absorptiometry, which rather underestimates bone loss.
-
Rev Assoc Med Bras (1992) · Nov 2021
Nonalcoholic fatty liver disease: scintigraphy in the diagnosis of steatohepatitis.
Nonalcoholic fatty liver disease is the most prevalent cause of chronic liver disease worldwide. Nonalcoholic steatohepatitis is associated with increased mortality rates due to the liver and cardiovascular diseases. The gold standard for discriminating nonalcoholic fatty liver disease activity and staging is the anatomopathological examination, which is an invasive method. In this regard, noninvasive methods, such as scintigraphy, have been under investigation. This study investigated the role of scintigraphy in the diagnosis of nonalcoholic steatohepatitis in obese patients with nonalcoholic fatty liver disease undergoing bariatric surgery. ⋯ Scintigraphy was not proven to be a useful method to differentiate patients with and without nonalcoholic steatohepatitis.