Revista da Associacao Medica Brasileira (1992)
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Our aim was to evaluate the participants with the COVID-19 scale in order to see the effects of the COVID-19 pandemic on people, which has affected the whole world along with our country, to be able to take the necessary precautions for the current pandemic and similar pandemics and to minimize the negative aspects globally. ⋯ Besides the COVID-19 pandemic affecting the whole society, we see that the women population and people who have chronic illnesses are going through much more fear and anxiety.
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Rev Assoc Med Bras (1992) · Oct 2021
Can serum 8-hydroxy-2'-deoxyguanosine levels reflect the severity of pulmonary arterial hypertension?
Oxidative stress plays a pivotal role in the pathogenesis of pulmonary arterial hypertension. 8-Hydroxy-2'-deoxyguanosine is a sensitive biomarker that reflects the degree of oxidative damage to DNA. We investigated whether serum 8-Hydroxy-2'-deoxyguanosine is a clinically useful biomarker for the severity of pulmonary arterial hypertension. ⋯ The 8-Hydroxy-2'-deoxyguanosine levels were significantly correlated with exercise capacity (six-min walking distance) and symptomatic status (functional class), both of which show the severity of pulmonary arterial hypertension in patients.