Revista da Associacao Medica Brasileira (1992)
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Rev Assoc Med Bras (1992)
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Rev Assoc Med Bras (1992) · Mar 2020
Severe Cerebellar Degeneration and Chiari I Malformation - Speculative pathophysiology based on a systematic review.
Symptomatic Chiari Type I Malformation (CM) is treated with posterior fossa decompression with or without duroplasty. We have noticed some cases with concomitant severe cerebellar ataxia due to cerebellar atrophy. The aim of this study is to review the literature of CM associated with severe cerebellar atrophy and discuss its potential physiopathology. ⋯ Severe cerebellar atrophy is found in some patients with CM. Although chronic ischemia due to compression is the most presumed cause, other etiologies were proposed. The real reasons for cerebellar degeneration are not known. Further studies are necessary.