Revista da Associacao Medica Brasileira (1992)
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Rev Assoc Med Bras (1992) · Mar 2020
Analysis of the chemerin and resistin adipokines in children and adolescents.
To compare the serum concentrations of adipokines resistin and chemerin in children and adolescents with eutrophic and overweight and to evaluate their relationship with anthropometric, biochemical, and blood pressure variables. ⋯ the adipokines analyzed presented a distinct profile in the groups of children and adolescents with eutrophic and overweight.
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Rev Assoc Med Bras (1992) · Mar 2020
Factors related to adherence to antiretroviral treatment in a specialized care facility.
The objective of this study was to verify the level of adherence to antiretroviral treatment and its associated factors. This is a descriptive cross-sectional study based on data retrieved from medical records. To achieve this, we used a questionnaire composed of sociodemographic and clinical information recorded from patients aged between thirteen and fifty-nine years who attended a specialized service from 2007 to 2014. ⋯ Among the six variables selected for the multivariate model, cases of aids (p<0.001) remained significant. We concluded that having aids decreases the probability of non-adherence to antiretroviral treatment by 92%. These results indicate that symptomatic patients have better adherence to therapy.
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Rev Assoc Med Bras (1992) · Mar 2020
Challenges on participation in a cooperative group of childhood renal tumors in Brasil.
Children with renal tumors included in clinical trials have significantly better outcomes. In Brasil, the enrollment of patients in clinical trials remains challenging. Here we aimed to describe participation accrual in the Brazilian Wilms Tumor Study Group (BWTSG) and to identify barriers to trial registration of children with renal tumors. ⋯ Our results demonstrated low accrual of participation in a cooperative group trial in Brasil. We identified variations in registration rates according to geographic region and hospital, which may help targeted efforts to increase registration rates. The survey responses demonstrated that colleagues understand the importance of trial participation.
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Melatonin has anti-inflammatory and antioxidant properties that can influence tissue growth and apoptosis. This aspect may influence the success of organ transplantation. To evaluate the relationship between melatonin and organ transplantation. ⋯ Studies show that melatonin can reduce organ and species dependence, and the use of melatonin decreases graft rejection.