Journal of thrombosis and haemostasis : JTH
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J. Thromb. Haemost. · Jun 2015
Observational StudyEarly hemostatic responses to trauma identified with hierarchical clustering analysis.
Trauma-induced coagulopathy is a complex multifactorial hemostatic response that is poorly understood. ⋯ Hierarchical clustering analysis identified three distinct hemostatic responses to trauma. Further insights into the underlying hemostatic mechanisms responsible for these responses are needed.
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J. Thromb. Haemost. · Jun 2015
Recurrent venous thromboembolism in anticoagulated patients with cancer: management and short-term prognosis.
Recommendations for management of cancer-related venous thromboembolism (VTE) in patients already receiving anticoagulant therapy are based on low-quality evidence. This international registry sought to provide more information on outcomes after a breakthrough VTE in relation to anticoagulation strategies. ⋯ Morbidity and mortality are high after recurrence of cancer-related VTE despite anticoagulation. Further treatment appears to be more effective with LMWH than with a VKA.