Circulation
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Multicenter Study
Implementation of the fifth link of the chain of survival concept for out-of-hospital cardiac arrest.
The American Heart Association 2010 resuscitation guidelines recommended adding a fifth link (multidisciplinary postresuscitation care in a regional center) to the previous 4 in the chain of survival concept for out-of-hospital cardiac arrest. Our study aimed to determine the effectiveness of this fifth link. ⋯ URL: http://www.apps.who.int/trialsearch. Unique identifier: UMIN000001607.
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Despite several advances in postresuscitation care over the past decade, population-based mortality rates for patients hospitalized with cardiac arrest in the United States have not been studied over this time period. The aim of this study was to determine the annual in-hospital mortality rates of patients with cardiac arrest from 2001 to 2009. ⋯ The in-hospital mortality rate of patients hospitalized with cardiac arrest in the United States decreased by 11.8% from 2001 to 2009.
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Editorial Comment
Limb ischemia protects against contrast-induced nephropathy.
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Randomized Controlled Trial Comparative Study
Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) randomized trial.
Dabigatran reduces ischemic stroke in comparison with warfarin; however, given the lack of antidote, there is concern that it might increase bleeding when surgery or invasive procedures are required. ⋯ URL: http://www.clinicaltrials.gov. Unique identifier: NCT00262600.