The Journal of bone and joint surgery. American volume
-
J Bone Joint Surg Am · Jul 2006
Comparative StudyPlate fixation of ununited humeral shaft fractures: effect of type of bone graft on healing.
Delayed union or nonunion of a fracture of the humerus is an infrequent but debilitating complication. Open reduction and internal fixation combined with autologous bone-grafting can result in reliable healing of the fracture; however, there is morbidity associated with the bone-graft donor site. This study was designed to evaluate healing of ununited fractures of the humeral shaft treated by one surgeon at one institution with a strict and consistent surgical protocol but with the use of two different types of bone graft: autologous iliac crest bone graft and demineralized bone matrix. ⋯ Therapeutic Level III. See Instructions to Authors for a complete description of levels of evidence.
-
J Bone Joint Surg Am · Jul 2006
Comparative StudyLateral acetabular growth stimulation following a labral support procedure in Legg-Calve-Perthes disease.
The main goal of containment treatment in cases of Legg-Calvé-Perthes disease is to prevent hip deformity, which leads to arthritis in adulthood. Recently, the shelf arthroplasty (the labral support procedure) has been proposed as a method of containment. The purpose of the present study was to evaluate growth stimulation of the acetabulum in patients with unilateral Legg-Calvé-Perthes disease by measuring acetabular depth and height following treatment with the labral support procedure. Uninvolved, contralateral hips and hips that were treated with proximal femoral varus osteotomy were used to compare growth. ⋯ Therapeutic Level III. See Instructions to Authors for a complete description of levels of evidence.
-
J Bone Joint Surg Am · Jul 2006
Recombinant human osteogenic protein-1 induces bone formation in a chronically infected, internally stabilized segmental defect in the rat femur.
Recombinant human osteogenic protein-1 (rhOP-1), combined with a collagen carrier, has been shown to induce new-bone formation in a variety of animal models. The purpose of the present investigation was to test the hypotheses that rhOP-1 would accelerate bone formation in an internally stabilized, chronically infected, critical-size defect in the rat femur and that this effect would be enhanced by the administration of systemic antibiotic. ⋯ The treatment of an infection at the site of a fracture often necessitates removal of internal fixation. However, internal fixation is needed for fracture stability. This study presents an intervention that may accelerate fracture-healing in the presence of infection and colonized hardware, thereby permitting earlier removal of the hardware and more timely and effective treatment of the infection.
-
J Bone Joint Surg Am · Jul 2006
Oncologic and functional outcome following sacrectomy for sacral chordoma.
Sacral chordoma is a rare, low to intermediate-grade tumor that poses substantial challenges in terms of timely diagnosis and adequate treatment. Few studies have examined the oncologic and functional outcomes of patients treated for sacral chordoma. ⋯ Therapeutic Level IV. See Instructions to Authors for a complete description of levels of evidence.