Acta neurochirurgica
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Acta neurochirurgica · Sep 2005
Clinical evaluation of the polypropylene-polyester knit used as a cranioplasty material.
The paper presents clinical evaluation of the polypropylene-polyester knit used as a cranioplasty material. ⋯ Codubix knitted polypropylene-polyester implant proved to be useful and a safe cranioplastic material.
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Acta neurochirurgica · Sep 2005
Magnetic resonance imaging in experimental subarachnoid haemorrhage.
We developed an MRI protocol to measure cerebrovascular diameter and blood flow velocity, and if we could detect cerebrovascular alterations after SAH and their impact on cerebral ischaemia. ⋯ We showed that it is feasible to detect alterations of in-vivo vessel diameter and blood flow velocities and their consequences for brain damage after experimental SAH in the rat. The growth of the infarct volume between day 0 and 2 after SAH and the parallel vasoconstriction suggest that delayed cerebral ischaemia after SAH occurs in rats and that this may be caused by vasoconstriction.
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Acta neurochirurgica · Sep 2005
Functional recovery after human umbilical cord blood cells transplantation with brain-derived neutrophic factor into the spinal cord injured rat.
There have been many efforts to recover neuronal function from spinal cord injuries, but there are some limitations in the treatment of spinal cord injuries. The neural stem cell has been noted for its pluripotency to differentiate into various neural cell types. The human umbilical cord blood cells (HUCBs) are more pluripotent and genetically flexible than bone marrow neural stem cells. ⋯ The HUCBs can differentiate into neural cells and induce motor function improvement in the cord injured rat models. Especially, the BDNF has effectiveness for neurological function improvement due to axonal regeneration in the early cord injury stage. Thus the HUCBs and BDNF have recovery effects of a moderate degree for cord injured rats.