Acta neurochirurgica
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Acta neurochirurgica · Jul 2009
Long-term implantation of deep brain stimulation electrodes in the pontine micturition centre of the Göttingen minipig.
To implant deep brain stimulation (DBS) electrodes in the porcine pontine micturition centre (PMC) in order to establish a large animal model of PMC-DBS. ⋯ DBS electrodes can be implanted for several weeks in the identified CRF-dense area resulting in a useful large animal model for basic research on micturition and the future clinical use of this treatment modality in neurogenic supra-pontine voiding disorders.