Fetal and pediatric pathology
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Fetal Pediatr Pathol · Oct 2012
Foreskin analysis of circumcised boys with and without previous topical corticosteroid.
Problems with the foreskin are common reasons for pediatric surgery consultations. We collected the foreskin of 40 patients for 2 years and these samples were divided into groups with and without previous topical corticosteroid. ⋯ Fibrosis was higher in patients who used topical corticosteroid. A histopathologic study of the foreskin may provide an additional analysis of patients undergoing circumcision and it can also improve the accuracy of surgical indication.
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Fetal Pediatr Pathol · Oct 2012
Case ReportsAggressive sinonasal natural killer/T-cell lymphoma mimicking refractory sinusitis in a 4-year-old boy.
Pediatric patients with nasal symptoms are common, and most of them usually have inflammatory diseases, such as sinusitis, chronic rhinitis, nasal polyp, or adenotonsillar hypertrophy. Rarely, however, these inflammatory symptoms may be associated with more sinister pathology. Recently, we experienced a case of a 4-year-old boy with sinonasal natural killer (NK)/T-cell lymphoma whose initial symptoms were of nasal obstruction and mucopurulent nasal discharge.
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Fetal Pediatr Pathol · Jun 2012
Review Case ReportsProteus syndrome: three case reports with a review of the literature.
Proteus syndrome (PS) is a rare, progressive disorder that manifests as asymmetric, disproportionate overgrowth affecting tissues derived from any germline layer. Cases of PS from 2005-2010 were retrieved from the pathology files at our institution. Two confirmed cases and one possible case of PS were identified. ⋯ Patient 3 demonstrated a cerebriform connective tissue nevus alone. These patients demonstrate the spectrum of presentations of PS. Much is left to learn about this disfiguring disease.
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Fetal Pediatr Pathol · Jan 2011
Case ReportsCommunity acquired methicillin-resistant Staphylococcus aureus preseptal cellulitis complicated by zygomatic osteomylitis, cavernous sinus thrombosis and meningitis in a healthy child.
We report a case of community-acquired meticillin-resistant Staphylococcus aureus (CA-MRSA) preseptal cellulitis complicated by zygomatic osteomyelitis, cavernous sinus thrombosis, meningitis, and necroziting pneumonia in a previously healthy two and half month old girl. This case exemplifies an aggressive and disseminated CA-MRSA infection with deep venous thrombosis in an infant without predisposing risk factors. The literature is reviewed and recommendations for management are provided.
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Fetal Pediatr Pathol · Jan 2011
Case ReportsSuccessful treatment with oral valganciclovir of primary CMV enterocolitis in a congenitally infected infant.
Cytomegalovirus (CMV) is the most common congenitally acquired viral infection in the United States and is associated with significant morbidity and mortality. Primary CMV enterocolitis is well documented in immunocompromised patients, but remains rare in congenitally acquired infections. ⋯ Case reports show varied dosing and length of treatment of either intravenously administered ganciclovir, orally administered valganciclovir, or a combination of both. We present a congenitally infected infant with primary CMV enterocolitis who was successfully treated with orally administered valganciclovir.