Clinical toxicology : the official journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists
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Clin Toxicol (Phila) · Aug 2013
Multicenter Study Comparative StudyBehavioral and physiologic adverse effects in adolescent and young adult emergency department patients reporting use of energy drinks and caffeine.
This pilot study assessed the prevalence of physiologic and behavioral adverse effects among adolescent (13-17 years) and adult (18-25 years) emergency department patients who reported energy drink and/or caffeinated-only beverage use within the 30 days prior to emergency department presentation. It was hypothesized that energy drink users would report more adverse effects than those who used only traditional caffeinated beverages such as coffee, tea, or soft drinks. ⋯ Energy drink users and substance users are more likely to report specific physiologic and behavioral adverse effects. Emergency department clinicians should consider asking patients about energy drink and traditional caffeine usage and substance use when assessing patient symptoms.
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Clin Toxicol (Phila) · Aug 2013
An analysis of energy-drink toxicity in the National Poison Data System.
Small studies have associated energy drinks-beverages that typically contain high concentrations of caffeine and other stimulants-with serious adverse health events. ⋯ About half the cases of energy drink-related toxicity involved unintentional exposures by children < 6 years old. Educational campaigns and legal restrictions on the sale of energy drinks were associated with decreasing calls to poison centers for energy drink toxicity and are encouraged.
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Clin Toxicol (Phila) · Aug 2013
Persistently elevated troponin I in paracetamol hepatotoxicity: association with liver injury, organ failure, and outcome.
An elevated troponin I (TnI) is associated with a poorer prognosis during critical illness. ⋯ An elevated TnI in the context of acute liver injury or liver failure following paracetamol overdose is associated with a significantly worse patient outcome but it is not an independent prognostic factor. Further studies should be undertaken to investigate the mechanism behind this elevated troponin association.
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Clin Toxicol (Phila) · Aug 2013
Hump-nosed pit viper (Hypnale hypnale) envenoming causes mild coagulopathy with incomplete clotting factor consumption.
Limited information exists on the coagulopathy caused by hump-nosed pit viper (Hypnale hypnale) envenoming. ⋯ Hump-nosed pit viper bites result in a mild coagulopathy which is usually not detected by a WBCT20. It is characterised by mild elevation of INR, low fibrinogen and Factors V and VIII which may be consistent with the venom containing a thrombin-like enzyme.