Clinics

The most recent articles from: Clinics (Sao Paulo) January 2025

Clinics · Jan 2025

Letter

Comments on the article "Olanzapine as a prophylactic antiemetic for preventing postoperative nausea and vomiting after general anesthesia: A systematic review and meta-analysis".

no abstract available

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Clinics · Jan 2025

Gyosaponin ameliorates sevoflurane anesthesia-induced cognitive dysfunction and neuronal apoptosis in rats through modulation of the PI3K/AKT/mTOR pathway.

Sevoflurane (Sev) is an inhalational anesthetic for surgical procedures where it can trigger cognitive dysfunction and neuronal apoptosis. Gyosaponin (GpS) was studied for its effects on brain morphology and cognitive behaviors in Sev-anesthetized rats. ⋯ GpS ameliorates Sev-induced neurotoxicity and cognitive dysfunction by modulating the PI3K/Akt/mTOR pathway and alleviating neuronal apoptosis and oxidative stress.

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Clinics · Jan 2025

CircRBM33 competitively binds miR-15a-5p to mediate EZH1 expression to ameliorate sepsis-induced acute lung injury.

The study was to investigate circRBM33 in septic acute lung injury (ALI). ⋯ CircRBM33 improves ALI in septic mice by targeting the miR-15a-5p/EZH1 axis.

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Clinics · Jan 2025

Corrigendum to "Exploration of the mechanism underlying the therapeutic effect of electroacupuncture at chengshan acupoint on post-hemorrhoidectomy anal pain: Insights from the mAChRs/IP3-Ca2+-CaM signaling pathway" [CLINSP 79 (2024) 10048].

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