Neuroscience bulletin
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Neuroscience bulletin · Mar 2007
Facial pain induces the alteration of transient receptor potential vanilloid receptor 1 expression in rat trigeminal ganglion.
To investigate the involvement of transient receptor potential vanilloid receptor 1 (TRPV1) in the facial inflammatory pain in relation to thermal hyperalgesia and cold pain sensation. ⋯ Facial inflammatory pain could induce hyperalgesia to noxious heat and cold stimuli, and result in increase of the numbers of TRPV1 positive TG neurons and the peripheral and central terminals of TG. These results suggest that the phenotypic changes of TRPV1 expression in small and medium-sized TG neurons and terminals might play an important role in the development and maintenance of TO-induced inflammatory thermal hyperalgesia and cold pain sensation.
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Neuroscience bulletin · Nov 2006
Clinical application of magnetic resonance neurography in peripheral nerve disorders.
Recent advances in the technology of magnetic resonance (MR) imaging (MRI) have made the diagnostic evaluations for peripheral nerve disorders shift from the clinical and physiological examination to the anatomical study. As a sensitive noninvasive tool, MR neurography could directly display high-resolution longitudinal and cross-sectional images of peripheral nerves, including nerve compression, nerve inflammation, nerve trauma, nerve recovery, and systemic neuropathies, thereby the morphology of intraneural and extraneural lesions can be visualized. ⋯ The purpose of this review is to overview how to evaluate peripheral nerve problems with MR neurography and its current limitations and advances in experimental MR research. The techniques for peripheral nerve MR neurography will also be discussed.