Obesity
-
Observational Study
Course of depressive symptoms and treatment in the longitudinal assessment of bariatric surgery (LABS-2) study.
To examine changes in depressive symptoms and treatment in the first 3 years following bariatric surgery. ⋯ Bariatric surgery has a positive impact on depressive features. However, data suggest some deterioration in improvement after the first postoperative year. LABS-2, #NCT00465829, http://www.clinicaltrials.gov/ct2/show/NCT00465829.
-
We sought to determine early life factors that predict body mass index (BMI) and overweight/obesity of children aged 2 years. ⋯ At 2 years of age, longer breastfeeding duration was associated with lower BMI, while greater TV viewing time was associated with higher BMI, after adjusting for other factors. Early introduction of solids and maternal overweight or obesity were independently associated with overweight or obesity.
-
Comparative Study
Tonic hyper-connectivity of reward neurocircuitry in obese children.
Obese children demonstrate less activation in prefrontal regions associated with self-control and inhibition when presented with food cues and advertisements. This study evaluates the differences between obese and healthy weight children in resting-state functional connectivity to these brain regions. ⋯ Previously published results demonstrated that obese children exhibit less activity in brain regions associated with self-control when viewing motivationally salient food advertisements. Here, it is shown that the obese children also have tonically greater input to these self-control regions from reward neurocircuitry. The greater functional connectivity between reward and self-control regions, in conjunction with weaker activation of self-control neurocircuitry, may render these children more susceptible to food advertisements, placing them at elevated risk for over-feeding and obesity.
-
Review Practice Guideline
Expert Panel Report: Guidelines (2013) for the management of overweight and obesity in adults.