Journal of hospital medicine : an official publication of the Society of Hospital Medicine
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The burden of RSV, hMPV, and PIV amongst hospitalized adults in the United States from 2016 to 2019.
Respiratory syncytial virus (RSV), human metapneumovirus (hMPV), and parainfluenza virus (PIV) hospitalize many people yearly. Though severe lower respiratory tract disease has been described in children, the elderly, and the immunocompromised, there is a gap in our understanding of RSV, hMPV, and PIV in hospitalized adults. We sought to evaluate the association of RSV, hMPV, and PIV with severe respiratory disease requiring noninvasive or mechanical ventilation and death in hospitalized adults in the United States. ⋯ RSV, hMPV, and PIV have a significant burden on hospitalized adults, even without classic risk factors.