Clinical journal of the American Society of Nephrology : CJASN
-
Clin J Am Soc Nephrol · Oct 2011
Urinary calprotectin and the distinction between prerenal and intrinsic acute kidney injury.
To date there is no reliable marker for the differentiation of prerenal and intrinsic acute kidney injury (AKI). We investigated whether urinary calprotectin, a mediator protein of the innate immune system, may serve as a diagnostic marker in AKI. ⋯ Accuracy of urinary calprotectin in the differential diagnosis of AKI is high. Whereas calprotectin levels in prerenal disease are comparable with healthy controls, intrinsic AKI leads to highly increased calprotectin concentrations.
-
Clin J Am Soc Nephrol · Oct 2011
Editorial CommentThe role of catalytic iron in acute kidney injury.