Clinical journal of the American Society of Nephrology : CJASN
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Clin J Am Soc Nephrol · Jul 2018
Multicenter StudyRisk Factors and Outcomes of Rapid Correction of Severe Hyponatremia.
Rapid correction of severe hyponatremia can result in serious neurologic complications, including osmotic demyelination. Few data exist on incidence and risk factors of rapid correction or osmotic demyelination. ⋯ This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2018_06_05_CJASNPodcast_18_7_G.mp3.
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Clin J Am Soc Nephrol · Jun 2018
Acute Kidney Injury and Risk of Heart Failure and Atherosclerotic Events.
AKI in the hospital is common and is associated with excess mortality. We examined whether AKI is also independently associated with a higher risk of different cardiovascular events in the first year after discharge. ⋯ AKI is independently associated with a higher risk of cardiovascular events, especially heart failure, after hospital discharge.
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Clin J Am Soc Nephrol · Jun 2018
Randomized Controlled Trial Multicenter StudyIncidence and Progression of Chronic Kidney Disease in Black and White Individuals with Type 2 Diabetes.
Type 2 diabetes and associated CKD disproportionately affect blacks. It is uncertain if racial disparities in type 2 diabetes-associated CKD are driven by biologic factors that influence propensity to CKD or by differences in type 2 diabetes care. ⋯ Black participants enrolled in a randomized controlled trial had lower rates of incident CKD compared with white participants. Rates of eGFR decline, microalbuminuria, macroalbuminuria, and kidney failure did not vary by race.
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Clin J Am Soc Nephrol · May 2018
Editorial CommentDoes the Kidney Biopsy Portend the Future of Nephrology?
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Clin J Am Soc Nephrol · May 2018
Multicenter Study Comparative Study Observational StudyAdd-On Antihypertensive Medications to Angiotensin-Aldosterone System Blockers in Diabetes: A Comparative Effectiveness Study.
In individuals with diabetes, the comparative effectiveness of add-on antihypertensive medications added to an angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker on the risk of significant kidney events is unknown. ⋯ Compared with thiazide diuretics, calcium channel blockers were associated with a lower risk of significant kidney events and a similar risk of cardiovascular events.