International journal of chronic obstructive pulmonary disease
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Int J Chron Obstruct Pulmon Dis · Jan 2015
Comparative StudyIncreased hypoxemia in patients with COPD and pulmonary hypertension undergoing bronchoscopy with biopsy.
Patients with pulmonary hypertension (PH) are considered to be at risk for complications associated with flexible bronchoscopy (FB), but data concerning the degree of PH are often lacking. We investigated whether COPD patients with PH who undergo bronchoscopy are at greater risk for complications. ⋯ PH is common among COPD patients undergoing FB. PH patients undergoing BAL and TBB are at higher risk of decreased O2 saturation than those without PH. Further studies should assess the risk among COPD patients with moderate-to-severe PH.
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Int J Chron Obstruct Pulmon Dis · Jan 2015
Clinical TrialBronchoscopic lung volume reduction by endobronchial valve in advanced emphysema: the first Asian report.
Endobronchial valve (EBV) therapy is increasingly being seen as a therapeutic option for advanced emphysema, but its clinical utility in Asian populations, who may have different phenotypes to other ethnic populations, has not been assessed. ⋯ EBV therapy was as effective and safe in Korean patients as it has been shown to be in Western countries. (
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Int J Chron Obstruct Pulmon Dis · Jan 2015
Comparative StudyDialectal influence on chronic pulmonary disease assessment test: the reliability and validity study.
Chronic obstructive pulmonary disease (COPD) patients living in many countries are familiar with local dialects rather than the official language. We, therefore, compare the reliability and validity of the COPD Assessment Test (CAT) in Thai and northern Thai dialect versions, in stable COPD patients living in the northern part of Thailand. ⋯ The two Thai versions of CAT were proven to be good clinical tools with high reliability and acceptable validity for assessing the quality of life of Thai COPD patients. However, the northern Thai dialect version is more suitable for evaluating COPD patients living in the northern part of Thailand.
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Int J Chron Obstruct Pulmon Dis · Jan 2015
A score to predict short-term risk of COPD exacerbations (SCOPEX).
There is no clinically useful score to predict chronic obstructive pulmonary disease (COPD) exacerbations. We aimed to derive this by analyzing data from three existing COPD clinical trials of budesonide/formoterol, formoterol, or placebo in patients with moderate-to-very-severe COPD and a history of exacerbations in the previous year. ⋯ SCOPEX incorporates easily identifiable patient characteristics and can be readily applied in clinical practice to target therapy to reduce COPD exacerbations in patients at the highest risk.
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Int J Chron Obstruct Pulmon Dis · Jan 2015
The effect of dietary antioxidant on the COPD risk: the community-based KoGES (Ansan-Anseong) cohort.
Dietary antioxidants have been suggested to have protective role against chronic obstructive pulmonary disease (COPD), but few prospective studies examined this relationship. The prospective study was conducted to evaluate the effect of dietary antioxidants on COPD risk and lung function in the Korean population. ⋯ Our results suggest the independent beneficial effect of antioxidants, particularly vitamins C and E, on COPD risk and lung function in men.