International journal of stroke : official journal of the International Stroke Society
The most recent articles from:
Int J Stroke
-
Hypothermia is a promising experimental treatment for acute ischemic stroke. Human trials are still at an early stage, with the focus now on using hypothermia in awake patients. Pethidine (meperidine) is the principle agent used to control shivering in humans; however, whether it has any modulating effects on the neuroprotective efficacy of hypothermia is unknown. ⋯ The effects of hypothermia in a model of focal ischemia are not affected by administration of pethidine.