International journal of gynaecology and obstetrics : the official organ of the International Federation of Gynaecology and Obstetrics
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Int J Gynaecol Obstet · Oct 2004
Randomized Controlled Trial Comparative Study Clinical TrialSublingual misoprostol versus methylergometrine for active management of the third stage of labor.
To compare the efficacy and side effects of sublingual misoprostol and intravenous methylergometrine for active management of third stage of labor. ⋯ Sublingual misoprostol appears to be as effective as intravenous methylergometrine in the prevention of postpartum hemorrhage. However, larger randomized studies are needed to advocate its routine use.
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Int J Gynaecol Obstet · Oct 2004
Randomized Controlled Trial Clinical TrialHigh and low dose oxytocin in augmentation of labor.
To compare the efficacy and safety of high dose oxytocin in the augmentation of labor. ⋯ The use of high dose oxytocin is associated with significantly shorter labor without any adverse fetal and maternal effects.
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Int J Gynaecol Obstet · Sep 2004
Randomized Controlled Trial Comparative Study Clinical TrialMisoprostol vs. oxytocin for induction of labor at term.
Efficacy of misoprostol was studied for induction of labor at term. Seventy patients were randomized to Group A (n = 36, oral misoprostol 50 microg four hourly to maximum of 5 doses) and B (n = 34, continuous oxytocin infusion). Induction-delivery interval was shorter with misoprostol (7.7 +/- 2.8 h against 14.3 +/- 4.8 h with oxytocin) but the rates of vaginal delivery, cesarean, neonatal outcome variables were similar. Hence, misoprostol is an effective agent for induction of labor at term.