JACC. Cardiovascular imaging
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JACC Cardiovasc Imaging · Apr 2010
Comparative StudyFeasibility of FDG imaging of the coronary arteries: comparison between acute coronary syndrome and stable angina.
This study tested the hypothesis that fluorodeoxyglucose (FDG) uptake within the ascending aorta and left main coronary artery (LM), measured using positron emission tomography (PET), is greater in patients with recent acute coronary syndrome (ACS) than in patients with stable angina. ⋯ This study shows that in patients with recent ACS, FDG accumulation is increased both within the culprit lesion as well as in the ascending aorta and LM. This observation suggests inflammatory activity within atherosclerotic plaques in acute coronary syndromes and supports intensification of efforts to refine PET methods for molecular imaging of coronary plaques.
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JACC Cardiovasc Imaging · Mar 2010
Multicenter StudyThe impact of obesity on the left ventricle: the Multi-Ethnic Study of Atherosclerosis (MESA).
The purpose of this study was to evaluate the relationship of left ventricular (LV) remodeling assessed by cardiac magnetic resonance to various measures of obesity in a large population-based study. ⋯ Obesity was associated with concentric LV remodeling without change in ejection fraction in a large, multiethnic cohort study.
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JACC Cardiovasc Imaging · Mar 2010
Multicenter StudyReproducibility of proximal isovelocity surface area, vena contracta, and regurgitant jet area for assessment of mitral regurgitation severity.
The aim of this study was to evaluate the interobserver agreement of proximal isovelocity surface area (PISA) and vena contracta (VC) for differentiating severe from nonsevere mitral regurgitation (MR). ⋯ The VC and PISA measurements for distinction of severe versus nonsevere MR are only modestly reliable and associated with suboptimal interobserver agreement. The presence of an identifiable effective regurgitant orifice improves reproducibility of VC and a central regurgitant jet predicts substantial agreement among multiple observers of PISA assessment.