Anaesthesiology intensive therapy
-
Anaesthesiol Intensive Ther · Jan 2019
Observational StudyChanges in topographic electroencephalogram during deepening levels of propofol sedation based on alertness/sedation scale under bispectral index guidance.
Sedation has been associated with numerous changes on electroencephalogram (EEG) but there is a need to clarify specific alterations in relation to deepening levels of sedation with different agents. We aimed to evaluate the effect of deepening levels of sedation induced by propofol and how they compare to natural sleep. ⋯ There are distinct changes associated with deepening levels of propofol induced sedation that distinguish it from natural sleep. This suggests that different mechanisms are involved in them and warrants further investigations to clarify the nature of these changes.