Circulation. Arrhythmia and electrophysiology
-
Circ Arrhythm Electrophysiol · Apr 2013
Randomized Controlled Trial Multicenter Study Comparative StudyPulmonary antrum radial-linear ablation for paroxysmal atrial fibrillation: interim analysis of a multicenter trial.
Substrate abnormality in pulmonary vein (PV) antrum plays a critical role in mechanism of atrial fibrillation (AF). The present study compares the strategy of PV antrum radial-linear (PAR) ablation to encircling PV isolation for paroxysmal AF. ⋯ URL: http://www.chictr.org; Unique identifier: ChiCTR-TRC-11001191.
-
Circ Arrhythm Electrophysiol · Apr 2013
Comparative StudyEffects of obstructive sleep apnea and its treatment on signal-averaged P-wave duration in men.
Prolonged P-wave duration, indicating atrial conduction delay, is a potent precursor of atrial fibrillation. Obstructive sleep apnea (OSA) is a risk factor for atrial fibrillation development. We investigated the association of P-wave duration with OSA and its treatment. ⋯ OSA severity was significantly associated with prolonged SAPWD. CPAP therapy significantly shortened SAPWD in patients with moderate-to-severe OSA. Thus, OSA may cause atrial conduction disturbances, leading to an increased risk of atrial fibrillation development, which may be modifiable by alleviating OSA with CPAP therapy.
-
Circ Arrhythm Electrophysiol · Apr 2013
Comparative StudyEffects of iatrogenic myocardial injury on coronary microvascular function in patients undergoing radiofrequency catheter ablation of atrial fibrillation.
Iatrogenic myocardial injury by radiofrequency catheter ablation (RFCA) releases proinflammatory substances from damaged myocardium, and these may contribute to endothelial dysfunction in systemic vascular structure. The aim of this study is to evaluate the effect of nonischemic myocardial damage on coronary microvascular function in patients undergoing atrial fibrillation (AF) ablation. ⋯ URL: http://cris.cdc.go.kr. Unique identifier: KCT0000030.