Endoscopy
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Patient controlled sedation (PCS) is becoming increasingly popular in day-case surgery and has the potential for use during endoscopy. We aimed to examine its safety and acceptability during colonoscopy in a pilot study using alfentanil and propofol and assess its influence on the patient's recovery time. ⋯ PCS with propofol and alfentanil is an effective, short-acting form of sedation for patients undergoing colonoscopy and may be an alternative to benzodiazepines.
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Randomized Controlled Trial Comparative Study Clinical Trial
A prospective, randomized controlled trial of sedation vs. no sedation in outpatient diagnostic upper gastrointestinal endoscopy.
The majority of gastrointestinal endoscopists in the United Kingdom routinely use intravenous sedation prior to diagnostic upper gastrointestinal endoscopy. We conducted a prospective, randomized controlled clinical trial to help determine whether the use of sedation influences the duration, safety, and tolerance of diagnostic upper gastrointestinal endoscopy. ⋯ In patients who are willing to contemplate upper gastrointestinal endoscopy without sedation, the avoidance of sedation may lead to faster and easier endoscopies, without any increased risk of procedural difficulties or adverse events.
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Randomized Controlled Trial Clinical Trial
Immediate recovery of psychomotor function after patient-administered nitrous oxide/oxygen inhalation for colonoscopy.
Previous studies have shown that patients inhaling-self-administered nitrous oxide/oxygen as a sedative/analgesic medication for colonoscopy were ready to leave the endoscopy unit on average sooner than those given conventional intravenous premedication. The aim of this study was to define the time course of recovery after nitrous oxide/oxygen sedation or intravenous opiate/benzodiazepine premedication for colonoscopy. ⋯ The rapid recovery observed with nitrous oxide/oxygen sedation for colonoscopy suggests that it is safe for patients to travel unescorted after the procedure. Driving may also be safe soon after nitrous oxide/oxygen sedation, but this requires further clarification.