Asian journal of psychiatry
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In current clinical practice, regardless of the clinical guidelines, BZDs and Z drugs are used beyond the period of indication, resulting in undesirable effects. This study aimed to assess feasibility of deprescribing amongst patients utilizing BZDs and Z drugs inappropriately for longer duration than the prescribed period. The study also analysed the Quality of Sleep (QoS) and Cost Savings incurred amongst deprescribed patients. ⋯ Deprescribing BZDs was associated with decline in its usage; implementing deprescribing practice amongst the inappropriate BZD users is feasible, provides an improved QoS and an economic benefit.
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Despite proven clinical utility, use of sublinugual buprenorphine is fraught with issues of potential diversion among patients with opioid dependence. Transdermal buprenorphine patches provide an alternative delivery model that can be utilized to reduce such diversion. This narrative review discusses the transdermal buprenorphine formulations, and its pharmacology, drug interaction and tolerability profile. The studies utilizing buprenorphine transdermal patches in the treatment of opioid dependence are examined, while the potential of using such patches for maintenance treatment of opioid dependence is examined.
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Alcohol consumption in India has been rising at an increasing rate. A better understanding of current trends of consumption and expenditure is necessary for tackling future challenges. ⋯ Households in India, on average, consumed 0.18 L of all alcoholic beverages per month (0.22 L in rural areas; 0.10 L in urban areas). The absolute quantity of alcohol consumed was higher among higher income-groups in both rural and urban areas. Country liquor was used by a majority across India; was used seven times more than toddy and beer, and 3.5 times more than Indian Made Foreign Liquor. Households' expenditure on alcohol was Rs.16.46 (US$0.26) per month, which was 0.98% of average total household MPCE. Fraction of average total household MPCE on alcohol in rural areas (1.14%) was almost double that of urban areas (0.62%). It increased steadily from lowest (0.5%) to highest (1.7%) income group in rural areas whereas in urban areas, it varied a little (0.5-0.8%) across income groups.