Injury
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The long-term risk of cardiovascular events caused by chronic kidney disease (CKD) is well described in the general population. Less is known concerning the risk of postoperative cardiovascular events in geriatric hip fracture patients with CKD. ⋯ Patients with CKD were more likely to have cardiovascular events after hip fracture surgery than those without CKD. Appropriate preoperative cardiovascular risk assessment and corresponding preventive and therapeutic measures should be given to this vulnerable population to mitigate such complications.
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To our knowledge, a vascularized bone flap training model has not been described in the literature. In this study, we hypothesized that chicken wing radius bone can be used as a cheap, realistic and easily accessible vascularized pedicled bone flap training model. ⋯ We think that this model can be a pioneer in defining the bone flap model in living animals in future studies. Since this inanimate animal model is a cost-effective and easily accessible technique, it offers the opportunity to be applied easily and repeatedly, even in the comfort of surgeons' homes.
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MiR-29a targets signal transducers and activators of transcription 3 (STAT3) and negatively regulates its expression. Both miR-29a and STAT3 have been implicated in sepsis and upregulated miR-29a was associated with sepsis. However, the regulation of miR-29a in sepsis is not well elucidated. ⋯ Histone acetylation promoted miR-29a expression, resulting in downregulation of STAT3 and exacerbation of sepsis.
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Patients with a lateral femoral wall (LFW) fracture were reported to have high rates of re-operation and complication. Although the LFW thickness was a reliable predictor of post-operative or intra-operative LFW fracture, there was a paucity of literature evaluating the critical stress distributions on the femur and screws of intertrochanteric fractures treated with dynamic hip screw (DHS). This study aimed to investigate the biomechanical performance of intertrochanteric fractures with different LFW thickness treated with DHS device. ⋯ The intertrochanteric fracture with a thinner LFW tended to have a higher risk of LFW fracture stabilized by a DHS device. Thus, the intertrochanteric fractures with a thinner LFW should not be treated by DHS alone and the intramedullary nail or an addition of trochanteric stabilization plate(TSP) was recommended.