Injury
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The COVID-19 pandemic has affected many habits and social reactions. During the lifting of COVID-19 lockdown measures in the USA, there was a notable surge in firearm violence, which became known as "the reopening phenomenon". This study evaluated the impact of a similarly proposed phenomenon on individuals living in a center of Türkiye. ⋯ The incidents analyzed predominantly involved the use of pistols (n = 371, 96 %). Long-barreled pistols caused injury in only 16 (4.1 %) cases. Most injuries (n = 275, 71 %) were located in the lower extremity. The comparison of the pre-pandemic, Pandemic lockdown and Reopening periods did not reveal a significant difference in the rate of firearm violence (p = 0.266, x2 goodness of fit) CONCLUSION: We did not observe the reopening phenomena around the COVID-19 pandemic period in a center of Türkiye. However, firearm violence remains a significant societal issue for both Türkiye and the world.
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The aim of this study is to evaluate the biomechanical efficiency of different miniplates in the treatment of multiple mandibula fractures. ⋯ Grid and ellipse plates provide successful results and plate geometry is more critical than number in terms of stress distribution.
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During osteogenesis, a large number of bioactive molecules, macromolecules, cells, and cellular signals are activated to induce bone growth and development. The activation of molecular pathways leads to the occurrence of cellular events, ultimately resulting in observable changes. Therefore, in the studies of bone tissue engineering and regenerative medicine, it is essential to target fundamental events to exploit the mechanisms involved in osteogenesis. ⋯ A combination of sequential cascades takes place to drive the progression of osteogenesis. Also, the occurrence of these processes and, more generally, cellular and molecular processes related to osteogenesis necessitate the presence of transcription factors and their activity. The present review focuses on outlining several signaling pathways and transcription factors influencing the development of osteogenesis, and describes various methods of their manipulation to induce and enhance bone formation.
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This study investigates the relationship between plasma exosomal miRNAs and nonunion risk following open reduction and internal fixation (ORIF) of clavicle fractures, aiming to identify predictive molecule to enhance patient management and personalized orthopedic care. ⋯ The elevated preoperative levels of exosomal miR-21 were significantly associated with an increased risk of bone nonunion at three months ORIF in patients with clavicle fractures, indicating that miR-21 holds potential as a non-specific predictive molecule.
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Current literature offers scant insights into Schatzker IV tibial plateau fractures (TPFs) that affect the posterolateral (PL) column. This study seeks to elucidate the prevalence of meniscal and ligamentous injuries in the knee, as well as the clinical outcomes, in Schatzker IV TPF cases, both with and without PL column involvement. ⋯ This investigation reveals that Schatzker IV TPFs involving the PL column are highly associated with increased rates of LM and ACL injuries. Additionally, these fractures correlate with a greater likelihood of knee subluxation and meniscus entrapment, ultimately leading to poorer prognostic outcomes.