Chest
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Editorial Comment
Successful Critical Care Operations: The Minnesota COVID-19 Experience.
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Associations between tobacco use and poor TB treatment outcomes are well documented. However, for important outcomes such as TB recurrence or relapse and mortality during treatment, as well as for associations with smokeless tobacco (ST), the evidence is not summarized systematically. ⋯ Tobacco use significantly increases the risk of TB recurrence or relapse and mortality during treatment among people with TB, highlighting the need to address tobacco use to improve TB outcomes.
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Multicenter Study Observational Study
Epidemiology and clinical patterns of Lung Abscesses in ICU: A French multicenter retrospective study.
Data are scarce regarding epidemiology and management of critically ill patients with lung abscesses. ⋯ Pulmonary abscesses in the ICU are a rare but severe disease often resulting from a polymicrobial infection, with a high proportion of Enterobacteriaceae, S aureus, and P aeruginosa. Percutaneous drainage, surgery, or arterial embolization was required in more than one-third of cases. Further prospective studies focusing on first-line antimicrobial therapy and source control procedure are warranted to improve and standardize patient management.
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Multicenter Study Clinical Trial
Comparative effectiveness of first-line and alternative antibiotic regimens in hospitalized patients with non-severe community acquired pneumonia: A multi-centre retrospective cohort study.
There are several antibiotic regimens to treat community-acquired pneumonia (CAP). ⋯ BL+M, FQ, and BL+D had similar outcomes and can be considered effective regimens for nonsevere CAP. Compared with BL+M, BL was associated with longer time to discharge and the CI for mortality cannot exclude a small but clinically important increase in risk.