Advances in nutrition
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Magnesium is the fourth most abundant mineral and the second most abundant intracellular divalent cation and has been recognized as a cofactor for >300 metabolic reactions in the body. Some of the processes in which magnesium is a cofactor include, but are not limited to, protein synthesis, cellular energy production and storage, reproduction, DNA and RNA synthesis, and stabilizing mitochondrial membranes. Magnesium also plays a critical role in nerve transmission, cardiac excitability, neuromuscular conduction, muscular contraction, vasomotor tone, blood pressure, and glucose and insulin metabolism. ⋯ Low levels of magnesium have been associated with a number of chronic diseases including migraine headaches, Alzheimer's disease, cerebrovascular accident (stroke), hypertension, cardiovascular disease, and type 2 diabetes mellitus. Good food sources of magnesium include unrefined (whole) grains, spinach, nuts, legumes, and white potatoes (tubers). This review presents recent research in the areas of magnesium and chronic disease, with the goal of emphasizing magnesium's role in disease prevention and overall health.
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Advances in nutrition · Mar 2013
ReviewSucrose, high-fructose corn syrup, and fructose, their metabolism and potential health effects: what do we really know?
Both controversy and confusion exist concerning fructose, sucrose, and high-fructose corn syrup (HFCS) with respect to their metabolism and health effects. These concerns have often been fueled by speculation based on limited data or animal studies. In retrospect, recent controversies arose when a scientific commentary was published suggesting a possible unique link between HFCS consumption and obesity. ⋯ Whether there is a link between fructose, HFCS, or sucrose and increased risk of heart disease, metabolic syndrome, or fatty infiltration of the liver or muscle remains in dispute with different studies using different methodologies arriving at different conclusions. Further randomized clinical trials are needed to resolve many of these issues. The purpose of this review is to summarize current knowledge about the metabolism, endocrine responses, and potential health effects of sucrose, HFCS, and fructose.
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Advances in nutrition · Jan 2013
Impact of new-generation parenteral lipid emulsions in pediatric nutrition.
Advancements in the care of premature infants and infants with severe bowel disease have occurred in which long-term use of i.v. nutrition is a cornerstone of successful therapy. Concern about the role of i.v. lipid emulsions in causing severe liver damage to high-risk infants receiving long-term i.v. nutrition has led to a variety of intervention strategies. ⋯ This result is supported by animal models of liver disease that demonstrate decreased liver damage when animals are provided omega-3 fatty acid-containing lipid emulsions compared with those primarily omega-6 fatty acid based. However, human trials are limited at this time and further research is needed to establish the best approach to preventing liver damage in infants receiving i.v. nutrition and the optimal dose and timing of intervention with novel lipid emulsions.
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Food insecurity is a leading public health challenge in the United States today. This is primarily due to the magnitude of the problem, ∼50 million persons are food insecure (i.e., they were uncertain of having, or unable to acquire, enough food because they had insufficient money or other resources), and the serious negative health and other outcomes associated with being food insecure. This paper defines the measure used to delineate whether a household is food insecure. ⋯ This makes it the largest food assistance program and the largest near-cash assistance program in the US. After defining the eligibility criteria, I review the literature, which has demonstrated the effectiveness of SNAP in addressing its key goal, namely the alleviation of food insecurity in the US. I conclude with 4 suggestions for how SNAP can maintain and even improve its effectiveness in alleviating food insecurity.