Stroke; a journal of cerebral circulation
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Genetic Factors Influencing Coagulation Factor XIII B-Subunit Contribute to Risk of Ischemic Stroke.
Abnormal coagulation has been implicated in the pathogenesis of ischemic stroke, but how this association is mediated and whether it differs between ischemic stroke subtypes is unknown. We determined the shared genetic risk between 14 coagulation factors and ischemic stroke and its subtypes. ⋯ Genetic markers associated with low FXIIIB levels increase risk of ischemic stroke cardioembolic subtype.