Revista española de medicina nuclear e imagen molecular
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Rev Esp Med Nucl Imagen Mol · May 2013
Case ReportsClinical impact of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the evaluation of small cell carcinoma of the prostate.
Small cell carcinoma of prostate (PSCC) is an uncommon and aggressive type of prostate malignancy with limited data on the use of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) in the clinical management of this rare entity. In this report, clinical and imaging findings of a patient with PSCC are presented. We aimed to discuss the role of PET/CT in the evaluation of PSCC in combination with histopathological characteristics of tumor and emphasize the importance of PET/CT in the clinical management of PSCC.
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Richter's syndrome (RS) refers to transformation of the chronic lymphoid leukemia (CLL) to a diffuse large cell lymphoma. Prognosis of patients with RS is generally considered unfavorable. We present two cases of patients with history of CLL, who had an increased of the lymphadenopathy, with elevated lactate dehydrogenase (LDH) in serum and increased (18)F-FDG uptake of the neck lymph nodes, with subsequent confirmation of RS by histology.