Anesthesiology
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Postoperative cognitive dysfunction is being increasingly reported as a complication. The authors investigated the role of cytokine-mediated inflammation within the central nervous system in the development of cognitive dysfunction in a rat model. ⋯ These results suggest that splenectomy performed during neuroleptic anesthesia triggers a cognitive decline that is associated with a hippocampal inflammatory response that seems to be due to proinflammatory cytokine-dependent activation of glial cells.
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Comment Letter Case Reports
Advanced cardiac life support for presumed bupivacaine-related cardiac arrest.
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Editorial Comment
"A razor may be sharper than an ax, but it cannot cut wood".