Anesthesiology
-
Anesthetic preconditioning is mediated by beta- adrenergic signaling. This study tested the hypotheses that desflurane-induced preconditioning is dose-dependently blocked by metoprolol and mediated by calcium/calmodulin-dependent protein kinase II (CaMK II). ⋯ Desflurane-induced preconditioning is dose-dependently blocked by metoprolol and mediated by CaMK II.
-
Comparative Study
High-throughput operating room system for joint arthroplasties durably outperforms routine processes.
Recent publications have focused on increased operating room (OR) throughput without increasing total OR time. The authors hypothesized that a system of parallel processing for lower extremity joint arthroplasties sustainably reduces nonoperative time and increases throughput. ⋯ Reorganizing the perioperative work process for total joint replacements sustainably increased OR throughput. Because joint arthroplasties generated a positive margin greater than the incremental cost, the high-throughput system improved financial performance.
-
Letter Case Reports
Maneuver to relieve kinking of the endotracheal tube in a prone patient.
-
Editorial Comment
Pharmacogenetics of nitrous oxide: standing at the crossroads.