Anesthesiology
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Acute lung injury is a common complication in critically ill patients. Several studies suggest that volatile anesthetics have immunomodulating effects. The aim of the current study was to assess possible postconditioning with sevoflurane in an in vivo model of endotoxin-induced lung injury. ⋯ Postconditioning with sevoflurane attenuates lung damage and preserves lung function in an in vivo model of acute lung injury.
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Review Meta Analysis
Serious complications associated with external intrathecal catheters used in cancer pain patients: a systematic review and meta-analysis.
Potential risks of intrathecal catheters in cancer patients include infection, bleeding, and neurologic injury. ⋯ Serious complications are rare in both hospitalized and homebound patients with intrathecal catheters. This analysis supports the reasoning that the potential benefit of intrathecal catheters in the treatment of severe cancer pain is likely to outweigh the potential for serious complications associated with this technique. Therefore, an external intrathecal catheter can be considered an effective and low-cost solution for the control of pain in such patients.
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Comment Letter
Hyperoxia in pediatric anesthesia: time for reconsideration?