Anesthesiology
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Myocardial energy metabolism is a strong predictor of postoperative cardiac function. This study profiled the metabolites and metabolic changes in the myocardium exposed to sevoflurane, propofol, and Intralipid and investigated the underlying molecular mechanisms. ⋯ Anesthetics and their solvents elicit distinct metabolic profiles in the myocardium, which may have clinical implications for the already jeopardized diseased heart.
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Biography Historical Article
Joseph Adrian Jeevendra Martyn, M.D., F.R.C.A., F.C.C.M., recipient of the 2010 Excellence in Research Award.