Anesthesiology
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Randomized Controlled Trial
Triple-low Alerts Do Not Reduce Mortality: A Real-time Randomized Trial.
Triple-low events (mean arterial pressure less than 75 mmHg, Bispectral Index less than 45, and minimum alveolar fraction less than 0.8) are associated with mortality but may not be causal. This study tested the hypothesis that providing triple-low alerts to clinicians reduces 90-day mortality. ⋯ Real-time alerts to triple-low events did not lead to a reduction in 90-day mortality, and there were fewer responses to alerts than expected. However, similar mortality with and without responses suggests that there is no strong relationship between responses to triple-low events and mortality.
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Editorial Comment
Succinylcholine and Dantrolene: Inseparable in the Emergency Cupboard?