Anesthesia and analgesia
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Anesthesia and analgesia · Feb 1995
Editorial CommentCoagulation and packed red blood cell transfusions.
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Anesthesia and analgesia · Feb 1995
Randomized Controlled Trial Clinical TrialVomiting after outpatient tonsillectomy and adenoidectomy in children: the role of nitrous oxide.
The role of nitrous oxide anesthesia in causing postoperative vomiting (POV) was studied in 60 children undergoing outpatient tonsillectomy and adenoidectomy. In this controlled, randomized, double-blind investigation, anesthesia was induced by inhalation of a volatile anesthetic in both groups. ⋯ Pharmacologic intervention was administered on the basis of evaluation by the nurses. Although a high incidence of POV was noted in both groups, there was no difference in either the incidence or the severity of POV between the group receiving nitrous oxide and the group receiving no nitrous oxide.
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Anesthesia and analgesia · Feb 1995
Randomized Controlled Trial Clinical TrialEfficacy of an epidural test dose in adult patients anesthetized with isoflurane: lidocaine containing 15 micrograms epinephrine reliably increases arterial blood pressure, but not heart rate.
When continuous epidural anesthesia is combined with general anesthesia, the only objective sign of intravascular migration of the epidural catheter are the increments of heart rate (HR) or arterial blood pressure after a local anesthetic test dose containing epinephrine. However, the efficacy of a simulated intravenous (IV) test dose in adult patients under general anesthesia has not been determined. Thirty adult patients were randomly assigned to one of two groups, each of which was anesthetized with 1% end-tidal isoflurane and nitrous oxide after endotracheal intubation. ⋯ In the epinephrine group, significant increases in HR compared with the baseline value were observed from 40 to 80 s after the IV test dose with a mean maximum HR increase of 24 +/- 2 bpm (mean +/- SEM) occurring at 48 +/- 3 s. However, 5 of 15 patients in the epinephrine group developed HR increments smaller than 20 bpm (sensitivity 67%). Since HRs were essentially unchanged in the saline group, specificity, positive predictive value (+PV), and negative predictive value (-PV) were 100%, 100%, and 75%, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)