Anesthesia and analgesia
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Anesthesia and analgesia · Dec 2006
Randomized Controlled TrialThe effects of melatonin premedication on propofol and thiopental induction dose-response curves: a prospective, randomized, double-blind study.
The effect of melatonin on the intraoperative requirements for i.v.anesthetics has not been documented. We studied the effect of melatonin premedication on the propofol and thiopental dose-response curves for abolition of responses to verbal commands and eyelash stimulation. ⋯ Melatonin premedication significantly decreased the doses of both propofol and thiopental required to induce anesthesia.
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Anesthesia and analgesia · Dec 2006
Randomized Controlled TrialContinuous femoral nerve analgesia after unilateral total knee arthroplasty: stimulating versus nonstimulating catheters.
Continuous femoral analgesia provides extended pain relief and improved functional recovery for total knee arthroplasty (TKA). Stimulating catheters may allow more accurate placement of catheters. ⋯ The use of stimulating catheters in continuous femoral nerve blocks for TKA does not offer significant benefits over traditional nonstimulating catheters.
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Anesthesia and analgesia · Dec 2006
Randomized Controlled TrialSmall-dose ketamine reduces the pain of propofol injection.
I.v. injection of propofol during anesthetic induction induces pain. Ketamine has been shown to reduce injection pain. In this study, we established the optimal dose of ketamine to prevent the pain of injection with propofol. ⋯ Administration of ketamine 100 microg/kg immediately before propofol injection provided the optimal dose and timing to reduce propofol-induced pain on injection.