Anesthesia and analgesia
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Anesthesia and analgesia · May 2009
Randomized Controlled Trial Multicenter Study Comparative StudyA randomized, double-blind, multicenter trial comparing transdermal scopolamine plus ondansetron to ondansetron alone for the prevention of postoperative nausea and vomiting in the outpatient setting.
Postoperative nausea and vomiting (PONV) are common complications after ambulatory surgery. We sought to determine whether the use of transdermal scopolamine (TDS) in combination with IV ondansetron (OND) is more effective than one alone for reducing PONV in outpatient settings. ⋯ TDS + OND reduces PONV compared with OND alone. This is achieved with a reduction in adverse events.