Anesthesia and analgesia
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Anesth. Analg.
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Anesthesia and analgesia · Jul 2021
Volutrauma Increases Exhaled Pentanal in Rats: A Potential Breath Biomarker for Ventilator-Induced Lung Injury.
Mechanical ventilation injures lungs, but there are currently no reliable methods for detecting early injury. We therefore evaluated whether exhaled pentanal, a lipid peroxidation product, might be a useful breath biomarker for stretch-induced lung injury in rats. ⋯ Exhaled pentanal is a potential biomarker for early detection of ventilator-induced lung injury in rats.