Anesthesia and analgesia
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Anesthesia and analgesia · Oct 2024
Clinical Decision Support as a Prevention Tool for Medication Errors in the Operating Room: A Retrospective Cross-Sectional Study.
Medication errors in the operating room have high potential for patient harm. While electronic clinical decision support (CDS) software has been effective in preventing medication errors in many nonoperating room patient care areas, it is not yet widely used in operating rooms. The purpose of this study was to determine the percentage of self-reported intraoperative medication errors that could be prevented by CDS algorithms. ⋯ Ninety-five percent of self-reported medication errors in the operating room were classified as preventable by CDS. Future research should include a randomized controlled trial to assess medication error rates and types with and without the use of CDS.
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Anesthesia and analgesia · Oct 2024
Historical ArticleFirst British and Irish Press Reports of Surgical Etherization.
In mid-December 1846, British and Irish newspapers reported the news of surgical etherization far more extensively than previously described. Reports about etherization had appeared at least 20 British and Irish newspapers in the days before Robert Liston's first operations under etherization on December 21, 1846. These reports were based on four separate accounts, 2 of which could be traced to New York, and 1 account had been published in a Parisian newspaper Galignani's Messenger on December 9, 1846.
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Anesthesia and analgesia · Oct 2024
Carboxyhemoglobin in Cardiac Surgery Patients and Its Association with Risk Factors and Biomarkers of Hemolysis.
Cardiac surgery with cardiopulmonary bypass (CPB) is associated with hemolysis. Yet, there is no easily available and frequently measured marker to monitor this hemolysis. However, carboxyhemoglobin (CO-Hb), formed by the binding of carbon monoxide (a product of heme breakdown) to hemoglobin, may reflect such hemolysis. We hypothesized that CO-Hb might increase after cardiac surgery and show associations with operative risk factors and indirect markers for hemolysis. ⋯ CO-Hb may represent a readily obtainable and frequently measured biomarker that has a moderate association with known biomarkers of and risk factors for hemolysis in on-pump cardiac surgery patients. These findings have potential clinical implications and warrant further investigation.
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Anesthesia and analgesia · Oct 2024
Classifying High-Risk Patients for Persistent Opioid Use After Major Spine Surgery: A Machine-Learning Approach.
Persistent opioid use is a common occurrence after surgery and prolonged exposure to opioids may result in escalation and dependence. The objective of this study was to develop machine-learning-based predictive models for persistent opioid use after major spine surgery. ⋯ The balanced random forest classifier was found to be the most effective model for identifying persistent opioid use after spine surgery.