Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · Jan 1995
[Hyperbaric surgery and oxygen therapy in clostridial myonecrosis].
116 patients with verified clostridial myonecrosis were treated by means of a regimen of combined cyclic hyperbaric oxygenation at 3 ata and repeated necrectomy. With proximal localization of gas gangrene in the elbow or knee (n = 55) 34.5% of patients survived, whilst with peripheral localization at the limbs (n = 44) the survival rate was 88.6% amputation being avoided in 21 of these cases. Abdominal localization (n = 17) was associated with the lowest survival rate (23.5%). In spite of severe clostridial toxicity in 80.1% of patients at the time of admission, the overall mortality was 50.8%.