Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · Dec 2003
Case Reports[The Tübingen palatal plate--an innovative therapeutic concept in Pierre-Robin sequence].
Infants with Pierre-Robin sequence (PRS) may suffer severe upper airway obstruction resulting in hypoxemia that is difficult to treat. We are currently evaluating a new therapeutic approach involving an oral appliance that widens the pharynx by pulling the base of the tongue forward using a preepiglottic baton. Here we present a patient treated with this device who showed a decrease in his desaturation index from 50 to < 1.
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Wien. Klin. Wochenschr. · Dec 2003
[Snoring as an sign of sleep disorders in 11- to 15-year-old school children--initial results of a Vienna epidemiologic study].
The prevalence of snoring was evaluated in school children between 11 and 15 years of age. In addition to items reported by parents, children were asked to answer a questionnaire in order to receive information about the children's potential complaints, life style and school performance. ⋯ The prevalence of snoring is lower in our study than in other studies. No statistically significant sex differences were observed, both in the parents' and the children's questionnaire. In our study snoring seems to be a sign or symptom of different sleep disorders, and not only of OSA. A statistically significant correlation between snoring and anamnestic hints of sleep disorders underlines the need to ask concerned children themselves for observations potentially associated with sleep disorders. Results of the Brouillette-Score could not be used to identify sleep disorders in our study.
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Wien. Klin. Wochenschr. · Dec 2003
Comparative StudyAngiotensin-converting enzyme genotype, albuminuria and plasma fibrinogen in type 2 diabetes mellitus.
Increased fibrinogen level is considered an important atherosclerosis risk factor. Patients with type 2 diabetes frequently have increased fibrinogen levels. The aim of the present study was to examine the effect of angiotensin-converting enzyme (ACE) gene polymorphism and the effects of the diabetic environment on plasma fibrinogen in type 2 diabetes. ⋯ ACE gene polymorphism is associated with plasma fibrinogen level in type 2 diabetes. This association is mediated by an interaction between ACE genotype and albuminuria. Diabetes patients with genotypes II or ID have increased plasma fibrinogen in the presence of albuminuria.