Headache
-
Alteration of circadian rhythmicity involving several endocrinologic and autonomic parameters has been observed in cluster headache. ⋯ Our findings suggest that in cluster headache there may be impairment of the pain control system that is associated with periodic failure of the mechanisms involved in the organization of biological rhythms.
-
We describe eight idiopathic cases of red ear syndrome in seven children and one adult. All were migraineurs with a history of paroxysmally painful and red ear, unilateral or alternating, in isolation or associated with migraine attacks. ⋯ Neurologic examination, brain MRI and CT scans, and x-rays of the cervical spine were normal. The close temporal relationship between the "red ear episodes" and migraine attacks suggests an association between the two conditions.
-
Evaluate the reduction in migraine-associated symptoms after administration of a single oral dose of almotriptan. ⋯ Almotriptan provides relief from migraine-associated symptoms of nausea, vomiting, photophobia, and phonophobia, and thus represents an attractive treatment option for a wide spectrum of migraine symptomatology.
-
Multicenter Study Clinical Trial
A long-term open-label study of oral almotriptan 12.5 mg for the treatment of acute migraine.
Evaluate the long-term tolerability of almotriptan 12.5 mg for the treatment of acute migraine attacks occurring over a 6-month period. ⋯ When taken at attack onset, almotriptan 12.5 mg is well tolerated, safe, and effective for the long-term treatment of acute migraine.