Journal of neurology, neurosurgery, and psychiatry
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J. Neurol. Neurosurg. Psychiatr. · Nov 2015
Lateralising value of experiential hallucinations in temporal lobe epilepsy.
Ever since John Hughlings Jackson first described the so-called 'dreamy state' during temporal lobe epilepsy, that is, the sense of an abnormal familiarity (déjà vu) or vivid memory-like hallucinations from the past (experiential hallucinations), these phenomena have been studied and repeatedly linked to mesial temporal lobe structures. However, little is known about the lateralising value of either déjà vu or experiential hallucinations. ⋯ These results suggest a lateralising value for experiential hallucinations to the left temporal lobe.
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J. Neurol. Neurosurg. Psychiatr. · Nov 2015
Extensive cerebral microbleeds predict parenchymal haemorrhage and poor outcome after intravenous thrombolysis.
Thrombolysis-related haemorrhagic transformation (HT) subtypes may have different prognostic implications. We aimed to analyse the impact of cerebral microbleeds (CMBs) burden on HT subtypes and outcome after intravenous thrombolysis. ⋯ The presence of extensive (≥ 3) CMBs increased the risk of PH 24 h after intravenous thrombolysis, and predicted poor clinical outcome independently.
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J. Neurol. Neurosurg. Psychiatr. · Nov 2015
Diagnostic accuracy of electrically elicited multiplet discharges in patients with motor neuron disease.
To determine and compare the diagnostic accuracy of electrically elicited multiplet discharges (MDs) and fasciculation potentials (FPs) in motor neuron disease (MND). ⋯ Electrically evoked MDs are highly specific for ALS and PMA and are an early sign of lower motor neuron dysfunction.
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J. Neurol. Neurosurg. Psychiatr. · Nov 2015
Comparative StudyImpaired imitation of gestures in mild dementia: comparison of dementia with Lewy bodies, Alzheimer's disease and vascular dementia.
To examine whether imitation of gestures provided useful information to diagnose early dementia in elderly patients. ⋯ Our study revealed that imitation of bimanual gestures was impaired non-specifically in about half of the patients with mild dementia, whereas imitation of finger gestures was significantly more impaired in patients with early DLB than in those with AD or SVaD. Although the sensitivity was not high, the imitation tasks may provide additional information for diagnosis of mild dementia, especially for DLB.
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J. Neurol. Neurosurg. Psychiatr. · Nov 2015
Interictal cerebral and systemic endothelial dysfunction in patients with migraine: a case-control study.
Although systemic endothelial function is unimpaired in migraine, it is unknown whether cerebral endothelial function impairment exists in migraineurs. ⋯ Migraineurs may have isolated cerebral endothelial dysfunction restricted to the posterior circulation in the absence of systemic endothelial dysfunction.