Journal of neurology, neurosurgery, and psychiatry
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J. Neurol. Neurosurg. Psychiatr. · Dec 2015
The temporal evolution of structural and functional measures after acute optic neuritis.
In this prospective case series, we aimed to characterise the temporal evolution of functional and structural measures in the afferent visual pathway of patients with acute optic neuritis (ON). ⋯ Structural and functional measures evolve over time in patients with ON. There may be sex-specific differences in recovery after an acute ON event.
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J. Neurol. Neurosurg. Psychiatr. · Dec 2015
Review Meta AnalysisMeta-analysis of modifiable risk factors for Alzheimer's disease.
The aetiology of Alzheimer's disease (AD) is believed to involve environmental exposure and genetic susceptibility. The aim of our present systematic review and meta-analysis was to roundly evaluate the association between AD and its modifiable risk factors. ⋯ Effective interventions in diet, medications, biochemical exposures, psychological condition, pre-existing disease and lifestyle may decrease new incidence of AD.
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J. Neurol. Neurosurg. Psychiatr. · Dec 2015
Review Meta AnalysisWernicke-Korsakoff syndrome not related to alcohol use: a systematic review.
Although Wernicke-Korsakoff syndrome (WKS) is a common condition, diagnosis remains difficult. WKS not associated with alcohol is rare and thought to present differently to alcohol-related WKS. We conducted a systematic review of WKS not related to alcohol to enhance understanding of WKS not related to alcohol and WKS in general. ⋯ Thiamine deficiency in the absence of an alcohol-use disorder can cause the full clinical spectrum of WKS, including chronic cognitive impairment and Korsakoff syndrome.