Journal of neurology, neurosurgery, and psychiatry
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J. Neurol. Neurosurg. Psychiatr.
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J. Neurol. Neurosurg. Psychiatr. · Aug 2019
High plasma concentrations of organic pollutants negatively impact survival in amyotrophic lateral sclerosis.
To determine whether persistent organic pollutants (POP) affect amyotrophic lateral sclerosis (ALS) survival. ⋯ Higher concentrations of POPs in plasma are associated with reduced ALS survival, independent of age, gender, segment of onset and other covariates. This study helps characterise and quantify the combined effects of POPs on ALS and supports the concept that environmental exposures play a role in disease pathogenesis.